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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '872e251fd0cd67d4b9a717a6c7d8b4711690b532c3767d48037e173f20355f3c' 
  AND token = '666pBpSvEHSvffhtAhcleu838wsisXvOdgytNpW9EDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}