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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4bb20a8b7bd4da4d591ffd4b466b73fb87e78b2e14183fbdca74690f65154af' 
  AND token = 'AhxxBJfh+2Ixe0nlRrFSYw1AfX5GE09jiPYsH5Vxpew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}