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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6336d5ab6dda8386aec3175338a4507eefd536df304ac5a2007b0f3f6a1168' 
  AND token = 'HqKSXNFxIo77zIkvd0jiNuspW9D5D32IeGEAcxLmDuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}