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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b8d814d799f333dc5dbbc63c5f03097aa40945ad3bed5bf5c96c7efa1e93a7' 
  AND token = 'o0NeMEqdiJNWESKzB4q3jeNtUvvVRityLsgfh0CcYMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}