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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a81bdb290ddd4c76f76f15826f5337fe9bacafae72441260fb6ac420dd6a3e5' 
  AND token = 'RzPoSfevyoPd31PZjyUB+km8C2ncIXefZ+IDO8toNVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}