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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be77a58ef03e2c7c1f33d9a30324fdb9171119c04bc4026d75bf567a2e51e87' 
  AND token = '5Ahjx9COZWZMhcaDyltF6rcCis+ecbDob4vCk80rxmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}