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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb185838cf8290b3bbe4f4c7b76403cbedc6468f3ef1420fca6192c1d2dcafb' 
  AND token = 'HfwrNcdHn9K5gdaDcdIjZz2aeGzMEpEjThF+04A4FDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}