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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e248c01f1dd300c10cdbfbc255b2f2cabb2d2e90c1a4e11e5f8747d5541427f' 
  AND token = 'BkR/2ygV425y4O3LyAObgO5IC8kSVRSuOO7DNQLNqG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}