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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e32534c5721a89dbb99355c05e38a053da072d01519d5d1f998ad51f5b6b90a' 
  AND token = 'qYdxdc9hAn/it6CD8PC0KgI4f3WiX5wjgKIsO4ca6Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}