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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb2eb7e5bda1800d94a41fef700da02f2cbebb2adcca63bca95a660737b4e523' 
  AND token = '9WAiHWEf2Iz+WhEIVejYkGkvNVTsTd+8kdt0Bv7s8nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}