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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33af551510c883c80b39f1fa8e5a7d31c889ad5ad78602fd51b91161954322b5' 
  AND token = 'D5KRkCKGdIsXVzopnz7B9CGF1QfWvAmGhQ8W4uA9Q5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}