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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e8410a57de5a40eb939332d8378d0159c76d3baa85509216267f324dd81dcd' 
  AND token = 'iR1hoMrZncW85ILqzyhf1PaSCEL095P1SaSGT2sIiCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}