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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8e64c4e39f598bfa5a9ee39fe5073a78f313d9664a42c8f50b94c5f77d004c' 
  AND token = 'trzPJW3nQxS+Wby9NWhXx8LbpZdIJ5z3pjGz3ReSd6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}