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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd26a1380221faeaa5e37d412b118fcdcb443577c9c193fcf8b485ec6780d096f' 
  AND token = 'MzcSrVeTZMmS3BlP0IPljtwgPU3dZOPBD9Tg5Sh9r9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}