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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d2f1125ab50be9064a85efff0c2103388fb4820599e39cdf9b5684485603b6' 
  AND token = '48deWcG1Pm4DJSmQAXKQLPJkw29hN69uGIUMaAHUt68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}