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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '858e3693e07b565130b1da329c35086a7686564f946a567f32b2251d1a9c5dab' 
  AND token = 'T6Y3taTScaAQNeQf2nSigIgp5nk3qVuupdJFDij6zQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}