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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600d0367795496efb5143ff25da34b33550eae2781a364f95564d4c44b49c17c' 
  AND token = 'zaI230HcrRBqq6O2MYP4p+EQjzteBeIvbInaRI43mHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}