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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a459d2a5a04af914d25d4b6a78738ffb1a6107fa2aaed007c12cc5b72e069ec' 
  AND token = 'a4IkkqCH/3msB87jbADnmdL9CxfEy66be610tH7/VoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}