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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454b5f70c1167b66d4a681669db61685d3abae889c1a404abc6a0da8a96cf9cf' 
  AND token = 'pt4oNv5Qnt9kc8bD2n8wA2hp4+xA7ceI81VapuN8L/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}