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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014422df5f62c8895beec13e7e259a09feb7ba8431f1d437935c3e22c0bda652' 
  AND token = 'yzU05sV1TftE8LfrU/z+wLKDUNxx4/KnT6RUjbGtKvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}