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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e59bb752a1d91b496323310054936cda36e0a0db870ce1f1fb1753504b2250ea' 
  AND token = 'WtihRl4+FeIhrsEvFvUCdJS7NEcH3BrNifOOgPgT2ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}