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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bc324b69277da2d65af31a2eb0a8f66a0d558579e0db226c8e43992fbfce1a' 
  AND token = 'CzE1SBg8UqyyQUgafSKquee9UWJK0YuSfpOtwsnt9eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}