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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3239562e371b89e9e5d8c813870c5271209749b23e830b9579d282d271422b04' 
  AND token = 'PhdFZof9/jUFpGdXK1WFzC5n4PNLKdyc+nOO1CGK5pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}