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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e468cf7d0f1922ed8825f6a0a1547f83f3ee65934639a4f411cf13fe64545992' 
  AND token = 'j3+x/PPfWnrVSVNlS0YqW88PTaluFsZHmPjNSMpMZnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}