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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '919db55f5ce24b954df585fe56ec0595a8f4f90b395d2c902c4ed4a8a2fb1de8' 
  AND token = 'U7/FV6l9fR/tZIOPPhN0+gmwd/WRE2QCzbv6Ky+UZno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}