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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b1b27e9386d5e4ebcc66ad29bb29fd1816f8a3fe2c9fc858dbf8189eee98a1' 
  AND token = 'wp9q4kRlt/m8Yxb7H3Y3xXXvZoTW1Eg3xl0FJp9aMRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}