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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7926865b3cb43c7a72c6629010c35e8939ed7aa6d87d778003b8429cf69f32a3' 
  AND token = 'LfAE/kzjzoCzZaOQIiNe49uIkYr4fcxuW2SFjM98csI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}