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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f249135f58adbf1b4897363ce319028b2377a917ba33a12c5ef7bed075bdb2' 
  AND token = 'WI3KelJkCt/LHpG2p9RIC+t6EiOBuJ65P1vU3qN95eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}