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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ed648dfa1ebbf1662e1781189b60a01dc8ccffc0594870ac35197ba1838845' 
  AND token = '5TYrynYdM91UME3u9eJwecFqEunz/xACZr1LxhaJ8IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}