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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ab59cf1b9588bc1cbf4863bf74b7e53464f3399d91502c33f29a6b04931d50' 
  AND token = '2FF0t8U7cYteqk1272kIUmOdHvtqmyd7QHJ47kO3lfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}