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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b248cc2a8cfcf18fdf08a6a4ed450f04953399d4f03d2ee477cd0458f4070e4' 
  AND token = 'ANBsH0I81qOfUvOQWNfywiWPu6LjzmRHzOwYX1c3WJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}