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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '040a3224828723639762432330c0022a16353df321cef794bdec2d6e05985ae1' 
  AND token = 'H25S8ULUXN2TcnUUbxM7GzKD/TxvFbG6qGfGRcRyaZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}