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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e5a845da3718669ba148967a114700e3d49bafb42c6bd8ae798bb9c995a281' 
  AND token = 'baf53eK+gi9x1haAKy3mauoNI65sOQp9xF09tI/YGpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}