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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e9e126c5346d9c51a397371a64fea77e7d1c9ede95c64f4aba813ed7d0c9d5' 
  AND token = 'ofHOQx0kRMmow5w2v7EafuOZcvhyiiRRC/Q6dm3AvZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}