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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1865fc8e83049414a346cc2287d048138c7d9ba314ccc449aaff892c5cf646c' 
  AND token = 'XnfrXUg056djHZSM+28+mre9K+EbfPr7VwCznLN9MT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}