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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e2b6ce2c02b331dca73df33f3b22153e7e399985489f3abf2b80cd9f44ded95' 
  AND token = '0NyNtKpP31NBS3fZGDMRqPBrmgisDO8jlbd+wd8xzGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}