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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e6fa7a0a3a75ad8b0ef683871624af6c2563afae9f1dcf2d064c8832c72a11' 
  AND token = 'gjK9x2ixJs92xddn8f/5BAjcbPH8dXjO/3NE+ZxZqn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}