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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491644116a04ba772b77040f6458a9e174d1ee4db35bc2d937d0efbb52700687' 
  AND token = '6MSlndCPHPQF7RoZ7Ypo5psyut55uHpCJDSYqeP9Pfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}