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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfe5a9ff2d68828ab404eb4b84a2a6c24d7b244b194edcc2e03454d4c591ce42' 
  AND token = 'HZxJ40Csd24Xs4eSBpFP7CtqkcYgYfGXaMmXzrt+r5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}