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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21841e73567a4e1e36fed009dcc1fe3e31160b653a178d01a39d877f2a90f0b4' 
  AND token = '3+ny+o3fFSwDoXCKWhWlmG1Y2berYSMHhb1z6l4YMvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}