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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d5a889d7cd1747eca8b6c33baf7f78f98427e5ca4b1c70f317e2659006718b0' 
  AND token = 'hJLnaI9Mcelmf9yS3yu7jGPtEPaLwJZ7krzCAz1QYA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}