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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe6cd3d2404a67b06e4bd6da69021a6eefcd7cc8c88ef08524e46d105d6eb5d' 
  AND token = 'XRTyieEU5YmpKMjMq63A7TUDZYitbyi4uXsqjvHs+tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}