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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd506986ddbe64cda7ff85c8fb8ccbef4a6b24518013cb4bab529e3fa9a47baab' 
  AND token = 'D6V19GJciB5pIx9qxDhG/eGPvDDsjgywrEv5+P762xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}