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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db5c117d87dc104dbbfa9f53288ffd9cf5d4c77901dd7a586fb3c833c10a6c5' 
  AND token = 'IRNXmsIaBJqaXI4gWtV0F69b3N5mmpyDqDk9udNXyZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}