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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0933362ccbb028883c2906f2a0fb6802a7dd3e3b7d1dda93a8ca5902bb68437f' 
  AND token = 'OkR2Qs3/dCln4v7v1IL1/WjdVG5EYcWUgOOkWysvSY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}