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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8bf32a5bbee2f1798d760cc4dbc37d01f004046d49809e6d0106537b0bf78c' 
  AND token = '6MKtpdqy16LjEuto7SIAvUEcCAt+OfNtMnD2a1YKmcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}