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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eaff7feefb8dafc85c528d3ce36eeef5cb02e99020711ee08d725c1d3f657ca' 
  AND token = 'HDrKI86+xT9OqW/FxPiRgIs7WebGWdhO4B/Oov8eoIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}