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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5c132676dc113db948563e1c5536d6c4e18a1ba5ec7f83b419078bd7214e11' 
  AND token = 'RBP8lXeegp+znWXWWr/q8PWFsJDEvu03TISZqyHiMGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}