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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e340f2a2d93e67caf7c7ccd78147fc3b7990e829cc88ebd8249ddefe90e597f3' 
  AND token = 'IDLVWHs+hfjoVw3j3NYWXosZtHaQUkU9bW3czjxkHvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}