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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666160b4bfc6b040c344914d563eac05fa0a74d23d6c0f1dd04a26d6a18ca16c' 
  AND token = 'cu9QR5sE6UQ4bd/ZPC0rQQxhbRLmsR+mRpSIQnL1SMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}